Summer is here! The sun is shining, days are becoming longer and the weather is so warm. Some people enjoy their vacations, for others, summertime just means spending more time outdoors with their friends and family. Medical aesthetics can help you get that summer glow look and have a flawless complexion. You can choose from a wide variety of cosmetic procedures, from dermal fillers to body sculpting.

Discovering Radiesse Dermal Fillers: The Ultimate Guide

With the growing demand for dermal fillers, the need for more refined solutions and advanced formulations increases. In this regard, Radiesse has gained a respected place in this market as a viable injectable in cosmetic dermatology. Being the only FDA-approved Calcium hydroxylapatite (CaHA) dermal filler, its popularity comes from a formula that boosts collagen and elastin production. 

Keep on reading to discover how this injectable smoothes out fine lines and what makes it a reliable product for aesthetic procedures. 

What is Radiesse?

Radiesse is a CaHA dermal filler manufactured by Merz Pharma. Injected in the different areas of the face and the back of the hands, the product reverses the aging signs. It smoothes moderate to severe wrinkles by adding volume. The product gained FDA approval in 2006 and has since been one of the most in-demand contouring gels with immediate yet long-lasting effects. 

What is Radiesse made of?

Radiesse consists of smooth spheres of calcium hydroxylapatite (CaHA) mixed into a gel-like substance made with sodium carboxymethylcellulose. These spheres have a size range of 25 to 45 micrometers and make up 30% of the filler. CaHA is found in the bones, indicating it is naturally occurring and hence the reason for the biocompatible nature of Radiesse. Moreover, this substance makes the injectable distinct from most other dermal fillers commonly made with hyaluronic acid (HA). 

How does Radiesse work?

Right after the injection of Radiesse, the gel fills in wrinkles and smoothes fine lines by adding volume. Next, the body absorbs the gel over time, but the compound triggers the skin cells called fibroblasts to start collagen production. In other words, except for volumization, the filler acts as a scaffold that restores elasticity and, in turn, helps the skin remain smooth for a long time. 

How long does Radiesse filler last?

The collagen synthesis stimulated by the filler prolongs the effects of Radiesse. The period of 12 -18 months is the usual lifespan of this injectable. Nonetheless, the effects can remain for up to two years, depending on the patient’s metabolism and the area of treatment.

What are the pros and cons of Radiesse filler?

The favorable results produced by Radiesse have made it one of the most reliable skin rejuvenation methods. Moreover, the CaHA gel has undergone several studies proving to be safe. Having said that, just like any other treatment, this FDA-approved injectable has its pros and cons. 


High safety profile and biocompatibility: Radiesse is made with a naturally occurring substance. This biocompatibility reduces the risk of allergic reactions. 

Immediate results: Radiesse volumizes the treated area upon injections, and the procedure does not require time to make its effects visible. 

Long-lasting results: Compared to hyaluronic acid dermal fillers, Radiesse usually lasts up to 12-18 months.

Minimally invasive with almost no downtime: Individuals receiving the treatment can resume their daily activities after the procedure ends


❌Granulomas:  Scarcely, small lumps or nodules called granulomas may form under the skin. These are usually temporary but may require treatment if they persist.

❌Allergic reactions: In rare cases, some individuals may experience allergic reactions. 

❌Temporary side effects: Swelling, bruises, redness, and tenderness are among the side effects in the injected areas.

❌Irreversible by treatment: Unlike hyaluronic acid dermal fillers, Radiesse is not dissolvable by substances such as Hyaluronidase. This means, in case of unfavorable results, the only solution is to wait until the body naturally breaks down the gel.

Considering all the pros and cons, a professional approach and a procedure performed under a certified healthcare provider are the best ways to maximize the benefits while minimizing the risks.

What is Radiesse used for?

Radiesse is commonly used in the face and the back of the hands and, more precisely:

  • Smile lines: Fills smile lines , known as nasolabial folds, to remove the expression that causes tiered and aged looks.
  • Corners of the mouth: Lifts the corners of the mouth (oral commissures) and pulls up the downturned appearance of the mouth, taking the angry or sad look away.
  • Marionette Lines: Smoothes the lines under the mouth (marionette lines), resulting in a refreshed look and a mouth that does not make an angry expression.
  • Pre-jowl Folds: Adds volume to the areas on either side of the chin to lift the skin and prevent sagging that may cause folds. 
  • Chin Wrinkles: Rejuvenates the chin and restores the beautiful smile of the young ages. 
  • Back of the hands: Adds volume to the back of the hands that have undergone the aging process and lost their elasticity. 
  • Deep scars: Fills in deep acne scars and brings the smooth-looking skin back to the appearance.
  • Volume loss: Plumps up the face that has suffered volume loss as a consequence of HIV. 

* The efficiency and safety of using Radiesse on the lips and around the eyes are still being researched.

How much does Radiesse cost?

The procedure cost may vary depending on the location, treatment frequency, and the practitioner performing the treatment. Regarding the product itself, the price of Radiesse ranges between $90 and $450. You can buy Radiesse online at more reasonable prices on ISLA MED.


Radiesse is a biocompatible dermal filler made with CaHA. Used in medical aesthetic procedures, it reverses aging signs and volume loss. Approved by the FDA, the injectable leaves long-lasting results due to its distinguishing function as a collagen and elastin stimulator. Wrinkles and folds of different grades around the mouth and nose are the main target of this CaHA-based filler. Despite being costlier than other dermal fillers in the market, Radiesse has proved to be a safe and practical treatment when injected by certified professionals. Explore the collection on ISLA MED and buy dermal fillers online.


Yes. Radiesse is the only CaHA dermal filler to have gained FDA approval.Yes. Radiesse is the only CaHA dermal filler to have gained FDA approval.

Calcium Hydroxylapatite (CaHA) is the main ingredient in the composition of the Radiesse. More precisely, it’s a compound consisting of 30% CaHA microspheres, measuring 25 to 45 micrometers in diameter, dispersed within a 70% water-based gel of carboxymethylcellulose.

No. Radiesse is a CaHA-based dermal filler that Hyaluronidase or any other dissolver cannot dissolve. Corrections are impossible if the procedure results in an unfavorable look or unwanted volume. This means you have to rely on the natural breakdown of the gel that happens over time (12-18 months).